View All Latest Cypress River Plantation 5000+ Sq. Ft. Properties for Sale

Welcome to 400 Chamberlin Road! This custom waterway home offers over 5500 heated square feet of beautifully curated space in the prestigious gated Cypress River Plantation community. Vaulted ceilings, built in cabinetry, detailed millwork, and gas fireplace all elevate the main living area and entryway of this stunning home. Chef style kitchen comes complete with 48" gas range/double oven combo, commercial size refrigerator, butler's pantry and oversized island perfect for entertaining. Just off the kitchen is a breakfast nook and keeping room with gas fireplace, powder room, laundry room and additional stairwell to access the second floor. Main level Owner's suite boasts a trayed ceiling, French doors that open to the covered rear patio and hot tub, master bathroom with spa like steam shower and jetted tub, dual sinks and marble vanity, water closet, and walk in master closet. Private study and formal dining room complete the main level floor plan. Second floor offers 2 guest rooms with shared jack and jill bath, an additional guest room with ensuite full bath, large game room with its own half bath, kitchen/bar area and private covered balcony. Other features include oversized 3 car garage, tankless water heaters, wi-fi thermostat, full home audio system, rear covered porch, screened in outdoor entertaining area with grill and outdoor fireplace, fenced in back yard, and private boardwalk and dock directly on the ICW. As a resident, enjoy all of the amenities that Cypress River Plantation has to offer including private boat launch, day dock, boat and RV storage, club house, pool, tennis courts, and more!

400 Chamberlin Rd., Myrtle Beach

Listing courtesy of Listing Agent: Allyson Springs (Cell: 843-442-9870) from Listing Office: Keller Williams Pawleys Island.

$1,650,000

6 Beds ⋅ 5 Baths ⋅ 2426288 MLS

Welcome to the epitome of luxury living! Nestled within the exclusive gated community of Cypress River Plantation, this stunning custom-made Mediterranean-style home boasts elegance and comfort at every turn. Positioned on a serene lakefront property with a fenced-in backyard, it offers both privacy and scenic views. As you enter through the grand foyer, you'll be immediately captivated by the soaring high ceilings and drawn to the circular staircase gracefully tucked within a turret. The layout of this exquisite 6-bedroom, 4 1/2-bathroom home is thoughtfully designed, featuring a 3-car garage for your convenience. Upstairs, an inviting loft awaits, complete with a wet bar, perfect for entertaining guests. Four bedrooms and a spacious bonus room, ideal for a theater room, provide ample space for family and friends. The master bedroom is a true sanctuary, highlighted by a cathedral ceiling and a generously-sized master bathroom featuring a walk-through shower, ensuring a lavish retreat at the end of each day. Embrace the southern lifestyle in your backyard oasis, tailor-made for entertainment and relaxation. A pool and hot tub beckon you to unwind, while the lanai, covered patio, and outdoor kitchen offer a seamless blend of indoor and outdoor living. Not just a home, but a lifestyle, this community's amenities are second to none. Residents enjoy access to a large community pool, a clubhouse, tennis courts, basketball courts, and a playground. For water enthusiasts, a private community boat launch into the Intracoastal Waterway awaits, along with boat/RV storage within the community. Plus, this home is only minutes to the beach. Seize the opportunity to live in this dreamlike Mediterranean-style home, where luxury, comfort, and a thriving community await. Don't miss your chance to experience the ultimate in refined living. Schedule a viewing today and let this home enchant you! Seller is licensed SC real estate agent. Some photos in this listing have been virtually staged.

2412 Gist Ln., Myrtle Beach

Listing courtesy of Listing Agent: Cristina Hudson (Main Line: 843-650-0998) from Listing Office: CB Sea Coast Advantage MI.

Selling Office: CB Sea Coast Advantage MI.

$3,300,000

6 Beds ⋅ 9 Baths ⋅ 2423613 MLS

Exclusive opportunity to own a luxurious 6-bedroom, 9-bathroom home directly on the Intracoastal Waterway, nestled on a private 0.97-acre lot. This home features every imaginable amenity, including a 4-car garage, elevator, and multiple indoor and outdoor living areas. With nearly 5,700 heated sq ft and 9,000 sq ft under roof, it offers expansive spaces for comfort and entertainment. Enjoy your own private dock, pool cabana, and more. The extraordinary extras make this home truly one-of-a-kind. Currently under construction by signature builder Fournier Homes, this property promises the highest quality of craftsmanship. Located in the gated community of Cypress River Plantation, residents enjoy access to security, tennis courts, a clubhouse, private boat launch, and an RV and boat storage lot. This home offers versatility for various uses, featuring 10 ft custom doors, zero-turn sliders, and much more. Contact us for more information on this rare and exceptional opportunity.”

372 Chamberlin Rd., Myrtle Beach

Listing courtesy of Listing Agent: The Davis Team (Cell: 843-421-5483) from Listing Office: EXP Realty LLC.

Selling Office: RE/MAX Executive.

Start Your Search

Provided courtesy of The Coastal Carolinas Association of REALTORS®. Information Deemed Reliable but Not Guaranteed. Copyright 2026 of the Coastal Carolinas Association of REALTORS® MLS. All rights reserved. Information is provided exclusively for consumers’ personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.

5000+ Sq. Ft. Cypress River Plantation Real Estate

Our website features the best real estate search for 5000+ sq. ft. properties available in Cypress River Plantation and surrounding areas. It is the only site you will ever need! It is easy-to-use and updated by the official Realtor®’s database every 15 minutes.

You can save searches, and get daily email alerts of new listings, price changes, sold data, and market reports. Our Interactive Map Search allows you to view properties on a map or refine your search by drawing the boundaries around the area you desire.

Curious about what’s happening in your neighborhood? You can create a custom market report to see what’s active, under contract, and sold in your neighborhood!

Considering selling or refinancing your home? Get an INSTANT property valuation now!